Melissa Mark, MD



American Board of Pediatrics Hospice/Palliative Care Pediatric Hematology-Oncology



Medical School:

Eastern Virginia Medical School


Children's Hospital of The King's Daughters


Cincinnati Children’s Hospital Medical Center


Dr. Mark completed fellowship at Cincinnati Children’s Hospital Medical Center in pediatric hematology/oncology, with a focus on brain tumors in addition to a fellowship in pediatric palliative care. During her fellowship in Cincinnati, Dr. Mark also completed a masters in clinical research where she focused on evaluation of symptoms and quality of life in pediatric cancer patients. Dr. Mark is a passionate advocate for the integration of palliative care as a standard of care in pediatric oncology and has spoken on this topic nationally. Her clinical focus is on pediatric brain tumors and she is excited to continue to grow the CHKD’s pediatric brain tumor program, including expanding access to clinical trials locally. CHKD is a return to her roots; it is where she completed her residency training after attending Eastern Virginia Medical School. She also serves as co-medical director for EdMarc Hospice for Children here in Hampton Roads.

Clinical Interests:

  • Pediatric brain tumors
  • Pediatric palliative care


  • Pain and symptom management
  • Health-related quality of life
  • International DIPG Registry

Honors and Awards:

  • Coastal Living Magazine “Top Doc” 2019, 2020, 2021, 2022, 2023
  • Robert Campe Goodan and Agusta S. Goodman Award in Recognition of Academic Excellence and Unselfish Concern for Others
  • Chief Fellow, Cincinnati Children’s Hospital
  • Rubio/Koehl Resident Teaching Award
  • Hyundai Hope on Wheels Grant Recipient
  • AAP CATCH Grant Recipient



  • Gurunathan A, Boucher AA, Mark M, Prus KM, O’Brien MM, Breese EH, Mizukawa BE, Absalon MJ, Nelson AS, Jordan MB, Grimley MS, Lorsbach RB, Rotz SJ, Mathanda R, Kumar AR. Limitations of HLH-2004 Criteria in Distinguishing Malignancy-Associated Hemophagocytic Lymphohistiocytosis. Accepted for publication in Pediatric Blood & Cancer on 7/18/18. DOI:10.1002/pbc.27400.
  • Thienprayoon R, San Julian Mark M, Grossoehme D. Provider-Prioritized Domains of Quality in Pediatric Home-Based Hospice and Palliative Care: A Study of the Ohio Pediatric Palliative Care and End-of-Life Network. J Palliat Med. 2018 Mar;21(3):290-296. doi: 10.1089/jpm.2017.0333. Epub 2017 Sep 22. PubMed PMID:28937333; PubMed Central PMCID: PMC5972768.
  • Mark M. What Mommy Does. J Clin Oncol. 2017 Mar 10;35(8):912-913. doi: 10.1200/JCO.2016.69.8738. Epub 2016 Dec 5. PubMed PMID: 27918715.
  • Shomaker K, Dutton S, Mark M. Pain Prevalence and Treatment Patterns in a US Children’s Hospital. Hosp Pediatr. 2015 Jul;5(7):363-70. doi: 10.1542/hpeds.2014-0195. PubMed PMID: 26136310.
  • Mark MS, Roseman JT, Caperton RL, Daniero JJ, Frontini M, Snaman JM. International volunteer medicine. JAMA. 2006 Aug 9;296(6):652; author reply 652-3. PubMed PMID: 16896105.

Community Involvement and Memberships:

American Society of Pediatric Hematology/Oncology

Children's Oncology Group

American Academy of Hospice and Palliative Medicine

American Academy of Pediatrics

Alpha Omega Alpha Medical Honor Society

EdMarc Hospice for Children

Contact Info:

(757) 668-7243



CHKD Main Hospital
601 Children's Ln
Norfolk, VA 23518



Children's Specialty Group

A team of healthcare providers dedicated to teaching, patient care and research because special families deserve special doctors!